Engineered EVs (EEVs) are an emerging form of precision medicine with immense promise and application in key areas such as neurology, cardiology and oncology. EEVs can be directed to certain cell types and carry powerful cargos, such as DNA, RNA, enzymes and/or small molecules. Because of their cellular provenance, EEVs avoid critical limitations of other delivery vehicles such as liposomes and other synthetic nanoparticles. Exopharm has a number of EEV projects under development.
Exopharm’s EEV technology includes EVPS to provide tissue tropism to exosomes and LOAD to load in active pharmaceutical ingredients (APIs) such as mRNA.